abstract：:The purpose of this study was noninvasive assessment of respiratory compliance and resistance in mechanically ventilated patients with acute respiratory failure (ARF). To this end, flow, change in lung volume, and airway pressure were measured at the proximal tip of the endotracheal tubes in twenty nine critically ill...

journal_title：Intensive care medicine

authors： Bernasconi M,Ploysongsang Y,Gottfried SB,Milic-Emili J,Rossi A

更新日期：1988-01-01 00:00:00

abstract：:A 29-year-old woman suffered a cardiac arrest, due to profound hyperkalaemia, caused by the use of a potassium-containing salt substitute. She was resuscitated, but post-hypoxic brain damage occurred. Some of the sparse literature is reviewed. ...

journal_title：Intensive care medicine

authors： Schim van der Loeff HJ,Strack van Schijndel RJ,Thijs LG

更新日期：1988-01-01 00:00:00

abstract：:The side effects of positive pressure ventilation on cardiovascular function are well known. However, in most clinical studies its influence on left ventricular function was examined. In the present study right ventricular (RV) performance was studied in 13 patients undergoing coronary artery bypass grafting during me...

journal_title：Intensive care medicine

authors： Neidhart PP,Suter PM

更新日期：1988-01-01 00:00:00

abstract：:A prospective study of thiamine status in patients with severe injuries (injury severity scores greater than 12) showed that they all developed signs of severe thiamine deficiency on the basis of transketolase activity, the standard biochemical test for thiamine deficiency. This occurred within the first week after th...

journal_title：Intensive care medicine

authors： McConachie I,Haskew A

更新日期：1988-01-01 00:00:00

abstract：:We evaluated the effect of a cimetidine continuous infusion (2 g in 24 h) on the intragastric pH of 16 critically ill patients (11 men, 5 women, mean age 45 years). During the 24 h pre-trial period and the subsequent 24 h cimetidine infusion, an intragastric combined electrode was placed in the fundus and the pH recor...

journal_title：Intensive care medicine

authors： Tomé G,Fiasse R,Reynaert M,Mahieu P,Hanssens F

更新日期：1988-01-01 00:00:00

abstract：:Placement of a Swan-Ganz catheter can cause many complications. This case report presents a new complication of Swan-Ganz catheter insertion--placement of the Swan-Ganz catheter tip in the coronary sinus. ...

journal_title：Intensive care medicine

authors： Baciewicz FA,Nirdlinger MA,Davis JT

更新日期：1987-01-01 00:00:00

abstract：:Acetazolamide (Diamox) induced carbonic anhydrase inhibition is an efficient means of eliminating surplus water and bicarbonate in the overhydrated and alkalotic patient. Previous studies have demonstrated an unexpected and unexplained increase in arterial and venous oxygenation during acute carbonic anhydrase inhibit...

journal_title：Intensive care medicine

authors： Berthelsen PG,Dich-Nielsen JO

更新日期：1987-01-01 00:00:00

abstract：:Peritonitis has been produced in rabbits by the spreading of 5 ml of caecal contents throughout the peritoneal cavity. After sacrifice at 5 h, electron microscopy revealed a increase of 600% in PMN and 1200% in lymphocytes in the pulmonary capillaries of the test animals when compared to the sham operated group. The p...

journal_title：Intensive care medicine

authors： Tighe D,Moss R,Parker-Williams J,Hynd J,Bennett ED

更新日期：1987-01-01 00:00:00

abstract：:Two hundred and seventy-three acute hemorrhagic shocks were treated in 1984 in a pre-hospital emergency care unit. Twenty patients (7%) had a paradoxical bradycardia: they were conscious, 9 of them had an undetectable systolic arterial pressure with the sphygmomanometric method but the femoral pulse was still present....

journal_title：Intensive care medicine

authors： Barriot P,Riou B

更新日期：1987-01-01 00:00:00

abstract：:Extracorporeal CO2-removal (EC-CO2-R) using a membrane lung system was applied for 12 and 20 days respectively in two young men with adult respiratory distress syndrome (ARDS). Neuropathological examination revealed only moderate hypoxic changes of unusual distribution. In the first case nerve cell loss in Sommer's se...

journal_title：Intensive care medicine

authors： Krajewski S,Seitz RJ,Schober R,Breulmann M,Falke KJ

更新日期：1987-01-01 00:00:00

abstract：:A case of brainstem encephalitis complicated by torsade de pointes is described. The possible occurrence of ventricular arrhythmias may contribute to the mortality in this condition. We recommend the admission of patients with brainstem encephalitis to an intensive care unit, for a period of electrocardiographic monit...

journal_title：Intensive care medicine

authors： De Keyser J,De Boel S,Ceulemans L,Ebinger G

更新日期：1987-01-01 00:00:00

abstract：:Nosocomial infections are a major problem in intensive care patients. Thirty-nine patients, requiring intensive care for 5 days or more (mean 15.8 days) were prospectively investigated, to determine the relation between colonisation and nosocomial infection. Thrice weekly, cultures from the oropharynx, respiratory and...

journal_title：Intensive care medicine

authors： Kerver AJ,Rommes JH,Mevissen-Verhage EA,Hulstaert PF,Vos A,Verhoef J,Wittebol P

更新日期：1987-01-01 00:00:00

abstract：:The influence of varying cardiac output (CO) on thermal-dye extravascular lung water (EVLW) was investigated in a total of 40 cardiac surgery patients before the onset of the operation. EVLW was measured by means of the double indicator dilution technique with indocyanine green as the non-diffusible indicator and a mi...

journal_title：Intensive care medicine

authors： Boldt J,Kling D,von Bormann B,Scheld HH,Hempelmann G

更新日期：1987-01-01 00:00:00

abstract：:Plasma colloid osmotic pressure (COP) has been calculated from both serum albumin concentration and plasma total protein concentration. These values have been compared to those measured directly using a membrane-transducer oncometer in a group of normal subjects, in a group of critically-ill patients with a variety of...

journal_title：Intensive care medicine

authors： Barclay SA,Bennett D

更新日期：1987-01-01 00:00:00

abstract：:We studied the effect of thiopental loading during resuscitation of 53 patients following cardiopulmonary arrest and compared the outcome with that found in 54 patients treated conventionally in the 30 previous months. Thiopental therapy (10 mg/kg i.v.) was begun within 30 min of the arrest once hemodynamic stability ...

journal_title：Intensive care medicine

authors： Monsalve F,Rucabado L,Ruano M,Cuñat J,Lacueva V,Viñuales A

更新日期：1987-01-01 00:00:00

abstract：:In a randomized clinical trial the prophylactic effects of locally administered antimicrobials on quantitative colonization and respiratory infections were studied in intubated patients with an expected period of mechanical ventilation of greater than 6 days. Nineteen patients received 50 mg of polymyxin B and 80 mg o...

journal_title：Intensive care medicine

authors： Unertl K,Ruckdeschel G,Selbmann HK,Jensen U,Forst H,Lenhart FP,Peter K

更新日期：1987-01-01 00:00:00

abstract：:In hypoxia sensitive cells and tissues, the rates of glucose and O2 consumption are inversely related (Pasteur Effect). Under O2 limiting conditions the demands for glucose (glycogen) in such cells may drastically rise as a means for maintaining ATP turnover close to normoxic rates; nevertheless ion and electrical pot...

journal_title：Intensive care medicine

authors： Hochachka PW

更新日期：1986-01-01 00:00:00

abstract：:The reliability of cardiac output estimation by thermodilution during artificial ventilation was studied in anesthetized pigs at the right side of the heart. The estimates exhibited a cyclic modulation related to the ventilation. The amplitude of the modulation was independent of the level of positive end-expiratory p...

journal_title：Intensive care medicine

authors： Jansen JR,Versprille A

更新日期：1986-01-01 00:00:00

abstract：:Intravenous bolus endotoxin elicits a marked but transient increase in plasma TxB2 and 6-keto-PGF1 alpha in a large number of species. A smaller, delayed and more prolonged increase in TxB2 and 6-keto-PGF1 alpha are reported in animals with septic shock, i.e., those with fecal peritonitis or cecal ligation. Thromboxan...

journal_title：Intensive care medicine

authors： Ball HA,Cook JA,Wise WC,Halushka PV

更新日期：1986-01-01 00:00:00

abstract：:A retrospective study of the medical records of 115 consecutive cases of meningococcal disease with 11 fatalities was carried out in order to evaluate the power of 15 clinical and laboratory variables available on admission in predicting a fatal outcome. On linear discriminant analysis, six variables showed a signific...

journal_title：Intensive care medicine

authors： Gårdlund B

更新日期：1986-01-01 00:00:00

abstract：:Activation of the complement system within the lung can lead to acute pulmonary damage and dysfunction. Based on a variety of experimental models it is now apparent that lung injury is related to complement-induced generation of oxygen derived free radicals from neutrophils and from macrophages. In addition to the oxy...

journal_title：Intensive care medicine

authors： Ward PA,Johnson KJ,Till GO

更新日期：1986-01-01 00:00:00

abstract：:Measurements of added inspiratory work (AIW) of breathing imposed by three different CPAP systems were performed in 10 patients. One system was a continuous flow system while the two others were demand flow systems separated from respirators (Ohmeda VD 101 and Draeger CPAP 800 devices). AIW was calculated from pressur...

journal_title：Intensive care medicine

authors： Viale JP,Annat G,Percival C,Bertrand O,Motin J

更新日期：1986-01-01 00:00:00

abstract：:One hundred and eighteen 20-g radial artery catheters were prospectively evaluated in 109 cardiovascular surgical patients. 0.024% papaverine in saline was used as a continuous flushing solution. Using the Doppler method, obstruction of the radial artery with the catheter in situ was found in 11 (9.8%) patients. Decan...

journal_title：Intensive care medicine

authors： Weiss BM,Gattiker RI

更新日期：1986-01-01 00:00:00

abstract：:A hypertensive crisis with an arterial blood pressure of 280/180 mmHg developed immediately after an apparently successful removal of a phaeochromocytoma. The blood pressure could not be lowered by phentolamine and not until the administration of dihydralazine and furosemide was the systemic pressure normalized. In ad...

journal_title：Intensive care medicine

authors： Johansson H,Brismar B,Hedenstierna G

更新日期：1986-01-01 00:00:00

abstract：:Thirty patients with adult respiratory distress syndrome required intermittent positive pressure ventilation; 15 survived. In 25 the syndrome followed bacterial infection or multiple injuries. From the peak upper airway pressure, the oxygen gradient and the age of the patient, an index was obtained which discriminated...

journal_title：Intensive care medicine

authors： Smith PE,Gordon IJ

更新日期：1986-01-01 00:00:00

abstract：:The goals of management of patients with respiratory failure include improving arterial oxygenation with PEEP and red cell transfusion to maintain oxygen carrying capacity, both of which contribute to improving tissue oxygen delivery. However, standard CPD-stored blood is rapidly depleted of 2,3 diphosphoglycerate (2,...

journal_title：Intensive care medicine

authors： Kahn RC,Zaroulis C,Goetz W,Howland WS

更新日期：1986-01-01 00:00:00

abstract：:Membranous laryngotracheobronchitis is a very serious infection which affects the larynx, trachea and bronchi, requiring aggressive therapeutic measures. It has been recently rediscovered as a cause of disease in children. However, it is a very unusual complication of measles. Two infants with measles and membranous l...

journal_title：Intensive care medicine

authors： Labay MV,Ramos R,Hervas JA,Reynes J,Gomez B

更新日期：1985-01-01 00:00:00

abstract：:We analysed the case histories of 22 patients with life threatening asthma retrospectively. Fifteen patients needed mechanical ventilation. Three patients, all of them in cardiac arrest before or at the moment of admission, died. In five patients, halothane therapy was successfully used as a last resort. No major comp...

journal_title：Intensive care medicine

authors： Rosseel P,Lauwers LF,Baute L

更新日期：1985-01-01 00:00:00

abstract：:Controlled mechanical ventilation is an accepted therapy for acute respiratory failure but by virtue of the increase in intrathoracic pressure has a large number of disadvantages. It is to overcome these disadvantages that alternative modes of ventilation have been introduced. These aim to reduce the effects of abnorm...

journal_title：Intensive care medicine

authors： Willatts SM

更新日期：1985-01-01 00:00:00

abstract：:We compare two patients admitted after near drowning. Both presented a severe metabolic acidosis, but only one of them developed an acute pulmonary edema with hypoxemia. An increase of lipid peroxides associated with a reduction of vitamin E concentration has been observed in this later patient. Lipid peroxidation, on...

journal_title：Intensive care medicine

authors： Bertrand Y,Artoisenet A,Allard B,Barbier B,de Meulder A,Raynaert M,Mathieu P,Dumont E

更新日期：1985-01-01 00:00:00

abstract：:Paediatric admissions to a general ITU are briefly reviewed. Although it may not be an ideal arrangement it is suggested that children can be safely cared for in such a unit. The problems created by the child with acute upper airway obstruction are discussed to demonstrate the way in which the unit is organized to rec...

journal_title：Intensive care medicine

authors： Eastham EJ,Papadatos J,Cook S,Stoddart JC

更新日期：1985-01-01 00:00:00

abstract：:A 16-month old baby developed severe respiratory failure because of acute laryngitis and required mechanical ventilation. Intubation was complicated by aspiration and development of chemical pneumonia. Following 4 days of treatment the child was successfully extubated. Thirty six hours after extubation the patient aga...

journal_title：Intensive care medicine

authors： Lotan C,Boneh A,Tamir I,Goitein KJ

更新日期：1985-01-01 00:00:00

abstract：:Two patients with chest injuries, flail chest and respiratory failure were mechanically ventilated by a system composed of 2 Bennett respirators and an independent source of gas. This system provides high-frequency positive pressure ventilation (HFPPV), low-frequency conventional mechanical ventilation (LFCMV) and hig...

journal_title：Intensive care medicine

authors： Barzilay E,Lev A,Lesmes C,Fleck R,Khourieh A

更新日期：1984-01-01 00:00:00

abstract：:Factors influencing nitrogen balance during total parenteral nutrition have been investigated in 34 critically ill injured patients studied during the first 6 days after trauma. Basal nitrogen balance was severely negative (-0.26 +/- 0.12 (SD) g X kg-1), but improved consistently during treatment. Nitrogen intake prov...

journal_title：Intensive care medicine

authors： Iapichino G,Radrizzani D,Solca M,Pesenti A,Gattinoni L,Ferro A,Leoni L,Langer M,Vesconi S,Damia G

更新日期：1984-01-01 00:00:00

abstract：:Changes in the inspiratory flow rate of mechanically ventilated patients can affect arterial oxygenation. Although the mechanism producing this alteration is not certain, one possible mechanism is a change in ventilation inhomogeneity. This study was performed to determine if the inspiratory flow setting would affect ...

journal_title：Intensive care medicine

authors： Felton CR,Montenegro HD,Saidel GM

更新日期：1984-01-01 00:00:00

abstract：:The Limulus amoebocyte lysate assay was used as one of a series of laboratory and clinical investigations on a group of 31 patients suffering from septic shock in order to assess the clinical significance of this assay for the detection of circulating endotoxin in clinical gram-negative sepsis. Four patients with card...

journal_title：Intensive care medicine

authors： McCartney AC,Banks JG,Clements GB,Sleigh JD,Tehrani M,Ledingham IM

更新日期：1983-01-01 00:00:00

abstract：:Six different types of continuous flush devices have been assessed for accuracy in vitro and ease of use in vivo. Only two types of device matched the manufacturers' specifications of performance. The other four gave higher flow rates than expected. ...

journal_title：Intensive care medicine

authors： Rithalia SV,Tinker J

更新日期：1983-01-01 00:00:00

abstract：:In 16 patients with multiple injuries the effect of parenteral administration of a fat emulsion on the pulmonary vascular system has been studied. Using the Hewlett Packard 5600 A Intensive Care System, which allows vital parameters to be sampled at a rate of two values per min, pulmonary artery pressure (PAP) was mon...

journal_title：Intensive care medicine

authors： van Deyk K,Hempel V,Münch F,Kopp M,Graf H,Epple E

更新日期：1983-01-01 00:00:00

abstract：:The effects of continuous and supplementary bolus dose administration of etomidate have been investigated in ten artificially ventilated patients in traumatic coma. Continuous infusion of etomidate (5-25 micrograms/kg/min) proved to be a practical and safe means of sedating these patients and appeared to control moder...

journal_title：Intensive care medicine

authors： Prior JG,Hinds CJ,Williams J,Prior PF

更新日期：1983-01-01 00:00:00

abstract：:The measurement of functional residual capacity (FRC) has assumed new importance in the diagnosis of acute respiratory failure. However few reference values exist for FRC in supine positions for both sexes. We measured the FRC in 100 healthy subjects with the helium dilution closed circuit method in the sitting and su...

journal_title：Intensive care medicine

authors： Ibañez J,Raurich JM

更新日期：1982-01-01 00:00:00